Tirzepatide
Mounjaro® · Zepbound®
The newest and most effective FDA-approved weight loss medication. Tirzepatide activates two hunger-regulating hormones at once — delivering results that exceed every other medication in its class.
What Is Tirzepatide?
Tirzepatide is the first in a new class of medications called dual GIP/GLP-1 receptor agonists. While semaglutide activates only the GLP-1 receptor, tirzepatide activates both GLP-1 and GIP — two gut hormones that work together to regulate appetite, insulin, and fat storage.
In the SURMOUNT-1 clinical trial — the most significant weight loss trial in decades — patients using tirzepatide lost an average of 22.5% of their body weight over 72 weeks, outperforming every prior medication and rivaling results seen with bariatric surgery.
SURMOUNT-1 Trial Results
Key Benefits
Up to 22% reduction in body weight — highest of any FDA-approved medication
Activates both GLP-1 and GIP hormone receptors simultaneously
Significantly greater weight loss than semaglutide alone in head-to-head trials
Powerful appetite suppression and reduced food cravings
Improves blood sugar, A1C, blood pressure, and triglycerides
Once-weekly injection with a simple auto-injector pen
FDA-approved for Type 2 diabetes (Mounjaro) and weight loss (Zepbound)
Effective for patients who plateaued or didn't respond to other GLP-1s
Is Tirzepatide Right for You?
Tirzepatide may be a good fit if you:
- Have a BMI ≥ 30, or ≥ 27 with a weight-related condition
- Want the highest level of efficacy currently available
- Have used semaglutide but want to try a more potent option
- Have Type 2 diabetes and want dual weight and blood sugar management
- Are committed to ongoing provider check-ins
Contraindications
Tirzepatide is not appropriate if you have:
- Personal or family history of medullary thyroid cancer
- Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
- History of severe pancreatitis
- Severe kidney or gastrointestinal disease
- Are pregnant or planning pregnancy
What to Expect: Dosing Timeline
Starting dose — allows your body to adjust and minimizes early side effects
First titration — noticeable appetite reduction begins
Significant hunger suppression, energy improvements common
Maintenance dose — maximum therapeutic effect at highest tolerated dose
Titration is gradual to minimize nausea and GI side effects. Your provider adjusts based on your response.
Start With a Consultation
We'll evaluate your eligibility, review your health history, and help determine whether tirzepatide is the right choice for your goals.